TY - JOUR T1 - Complicated pleural infection: Analysis of two consecutive cohorts managed with a different policy JO - Anales de Pediatría (English Edition) T2 - AU - Moral,L. AU - Loeda,C. AU - Gómez,F. AU - Pena,M.Á. AU - Martínez,M. AU - Cerdán,J.M. AU - Lillo,L. AU - Toral,T. SN - 23412879 M3 - 10.1016/j.anpede.2015.02.001 DO - 10.1016/j.anpede.2015.02.001 UR - https://www.analesdepediatria.org/en-complicated-pleural-infection-analysis-two-articulo-S2341287915000393 AB - IntroductionThe treatment of complicated pleural infection (CPI) is controversial. Clinical guidelines recommend drainage, but with the lowest grade of evidence. Recent reports have observed good outcomes with antibiotics alone. We retrospectively compared the outcomes in two consecutive cohorts treated with different policies: the first treated according to pleural fluid characteristics (2005–2009, interventional-prone, group 1) and the second according to clinical assessment (2010–2013, conservative-prone, group 2). MethodsThe clinical records of all children treated for CPI in our hospital between 2005 and 2013 were thoroughly reviewed. Primary outcomes were the proportion of children drained and the length of hospital stay (LHS). ResultsOne hundred and nine patients (64 group 1 and 45 group 2) were analyzed. A chest tube was placed in 83% of patients in group 1 and 47% in group 2 (P<0.001). The mean LHS was 11.4 days for patients in group 1 and 12.3 for patients in group 2 (P=0.45); no differences were observed in other outcomes. ConclusionOur results add to few recent observations reporting good outcomes in many children treated with antibiotics alone and challenge the need to drain most children with CPI. Clinical trials are now needed to identify when a drainage procedure would be useful. ER -