TY - JOUR T1 - Novel micro RNA-based therapies for the treatment of neuroblastoma JO - Anales de Pediatría (English Edition) T2 - AU - Boloix,Ariadna AU - París-Coderch,Laia AU - Soriano,Aroa AU - Roma,Josep AU - Gallego,Soledad AU - Sánchez de Toledo,Josep AU - Segura,Miguel F. SN - 23412879 M3 - 10.1016/j.anpede.2015.07.032 DO - 10.1016/j.anpede.2015.07.032 UR - https://www.analesdepediatria.org/en-novel-micro-rna-based-therapies-for-articulo-S234128791630014X AB - Neuroblastoma (NB) is the most common solid tumour in children and adolescents, and accounts for up to 15% of all cancer deaths in this group. It originates in the sympathetic nervous system, and its behaviour can be very aggressive and become resistant to current treatments. A review is presented, summarising the new alternative therapies based on epigenetics, i.e. modulators of gene expression, such as microRNAs and their potential application in the clinical practice of NB treatment. ER -