TY - JOUR T1 - Use of the 2D:4D digit ratio as a biological marker of specific language disorders JO - Anales de Pediatría (English Edition) T2 - AU - Font-Jordà,Antònia AU - Gamundí,Antoni AU - Nicolau Llobera,María Cristina AU - Aguilar-Mediavilla,Eva SN - 23412879 M3 - 10.1016/j.anpede.2018.02.008 DO - 10.1016/j.anpede.2018.02.008 UR - https://www.analesdepediatria.org/en-use-2d4d-digit-ratio-as-articulo-S234128791830173X AB - IntroductionThe finding of biological markers of specific language impairment would facilitate their detection and early intervention. In this sense, the 2D:4D finger ratio is considered an indirect indicator of prenatal exposure to testosterone. Previous studies have related it to linguistic competence and aggressive behaviour, and could be a candidate for a biological marker of language impairment. The aim was to compare the value of the 2D:4D ratio in children with Specific Language Impairment (SLI) with those of children with typical language development, as well as to establish to what extent this biological index correlates with the behaviour (linguistic, cognitive, social,...) in both groups. Subjects and methods2D:4D ratio, language, cognition and social behaviour were compared in a group of children with SLI (n=15), with a group of children without language difficulties (n=16) of the same age (between 5 and 8 years), gender (male), and socio-cultural level. ResultsChildren with SLI showed significantly higher values of 2D:4D ratio of the right hand, and a negative correlation between this ratio and their linguistic competence. Although the children with SLI showed impaired adaptive abilities, but not more aggressive behaviour, these measurements did not correlate with the 2D:4D index. Nevertheless, social behaviour correlated with language and cognition competence. ConclusionsA higher value of the biological 2D:4D ration (lower intrauterine exposure to testosterone) seems to be associated with language difficulties in boys with SLI, but not with their behavioural difficulties. Their behavioural difficulties seem to be a consequence of their linguistic difficulties and their level of cognition. ER -