TY - JOUR T1 - Continuous spike-waves during slow–wave sleep: Experience during 20 years JO - Anales de Pediatría (English Edition) T2 - AU - Escobar Fernández,Laura AU - Coccolo Góngora,Alejandra AU - Vázquez López,María AU - Polo Arrondo,Ana Paloma AU - Miranda Herrero,María Concepción AU - Barredo Valderrama,Estíbaliz AU - Castro de Castro,Pedro SN - 23412879 M3 - 10.1016/j.anpede.2018.12.004 DO - 10.1016/j.anpede.2018.12.004 UR - https://www.analesdepediatria.org/en-continuous-spike-waves-during-slowwave-sleep-articulo-S2341287919301346 AB - IntroductionContinuous spikes and waves during slow sleep (CSWS) is an EEG pattern that appears during childhood, and is often associated with cognitive impairment. It can appear in the course of epileptic syndromes, as well as in benign epilepsy. The aim of this study is to analyse epidemiological and clinical characteristics of patients with CSWS, in order to describe possible predictive factors in their outcome. MethodsA retrospective study was conducted on paediatric patients with CSWS treated in a third-level hospital from November 1997 to November 2017. ResultsThe study included 25 patients (68% male), of whom 76% had abnormalities in the neuroimaging or suffered from psychomotor development disorder (secondary CSWS). The rest were healthy, or diagnosed with idiopathic epilepsy. The mean age of onset of CSWS was 6.7 years, but earlier in the secondary CSWS cases. Symptoms were present during the CSWS episode in 72% of cases. All of them were treated with antiepileptic drugs, which were effective in 36%. CSWS stopped in 72%, and remission was longer if the CSWS onset occurred at an older age. One-third (33%) presented with sequelae, mostly cognitive and behavioural alterations. Outcome was poorer in those with secondary CSWS and, in those whose CSWS started at an earlier age and lasted longer. ConclusionThe CSWS pattern, although rare, is still a therapeutic challenge. A close follow-up of the patients with epilepsy is important, especially if associated with cognitive impairment, in order to establish an early diagnosis and treatment. ER -