TY - JOUR T1 - Recommendations for the diagnosis and practical management of paediatric eosinophilic oesophagitis JO - Anales de Pediatría (English Edition) T2 - AU - Gutiérrez Junquera,Carolina AU - Fernández Fernández,Sonia AU - Domínguez-Ortega,Gloria AU - Vila Miravet,Víctor AU - García Puig,Roger AU - García Romero,Ruth AU - Fernández de Valderrama,Ana AU - Andradas Rivas,Rebeca SN - 23412879 M3 - 10.1016/j.anpede.2020.04.005 DO - 10.1016/j.anpede.2020.04.005 UR - https://www.analesdepediatria.org/en-recommendations-for-diagnosis-practical-management-articulo-S2341287920300776 AB - Eosinophilic oesophagitis is an emerging and chronic disorder mediated by the immune system, and is characterised by symptoms of oesophageal dysfunction and inflammation with isolated eosinophil infiltration in the oesophagus. It is more common in males and in atopic subjects, and the symptoms vary with age. In younger children, there is vomiting, abdominal pain and dietary problems, with dysphagia and food impaction in older children and adolescents. The diagnosis is based on the presence of symptoms and oesophageal inflammation with ≥15 eosinophils/high power field, and after ruling out other causes of oesophageal eosinophilia. Without treatment, the disease usually persists and can progress to fibrostenotic forms more common in adults. The treatment options included proton pump inhibitors, empirical elimination diets, and swallowed topical corticosteroids. Maintenance therapy is advisable after the induction treatment. Diet is the only treatment that is directed at the cause of the disease, on identifying the triggering food or foods. The response to the treatments requires a histological assessment due to the poor agreement between the symptoms and the oesophageal inflammation.The practical management of Eosinophilic oesophagitis presents with challenges, due to, among other causes, the current lack of availability of specific drugs, and its approach with, occasionally complex, diet treatments. The present document, prepared by the Working Group on Eosinophilic Gastrointestinal Disorders of the Spanish Society of Paediatric Gastroenterology, Hepatology and Nutrition, has as its objective to help in the diagnostic and therapeutic approach to paediatric eosinophilic oesophagitis, based on the recent evidence-based consensus guidelines. ER -