Original ArticleVisual Outcomes in Children with Juvenile Idiopathic Arthritis–Associated Uveitis
Section snippets
Materials and Methods
The records of 269 patients, ages 1 to 17 years, who were examined and treated from 1985 through 2003 were reviewed. We identified 89 children with JIA-associated uveitis. Inclusion criteria for the study were ages 1 to 17, diagnosis of JIA by a pediatric rheumatologist, and presence of intraocular inflammation consistent with the signs and symptoms of JIA-associated uveitis. Patients who did not meet these criteria were excluded from the study. Variables assessed and analyzed included date of
Results
Of 269 children with uveitic syndromes referred to a tertiary eye center, 89 (33%) had JIA-associated uveitis. The process was bilateral in 76 children. Seventy-three patients (82%) were girls; 84%, Caucasian; 8%, African American; and 8%, Hispanic. Mean age of onset of uveitis was 5.7 years (range, 1–14). Mean follow-up for all children was 2.96 years. Antinuclear antibody positivity was detected in 56 patients, 44 of them female. Arthritis was oligoarticular in 88% of all patients, with a
Discussion
Reports have begun to appear in the literature reporting better visual outcomes of patients with JIA-associated uveitis.9, 12, 13, 14 Edelstein et al found in their study that only 6% of eyes of 163 patients ended with blindness.9 None of 63 patients in a Finnish study went blind from JIA-associated uveitis.12 Oren et al reported on 10 children, all of whom had final VA of 20/30 or better.13 Paroli et al found that 64.5% of their patients maintained VA of 20/33 or better at final follow-up.14
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Uveitis in Juvenile Idiopathic Arthritis: 18-Year Outcome in the Population-based Nordic Cohort Study
2021, OphthalmologyCitation Excerpt :In our study, 38.8% of the patients with JIA-U developed at least 1 ocular complication during the 18 years of observation. The rate of complications is lower than in previous reports 2 or more decades ago.15,16,40 However, complications are more prevalent in our study compared with other recent studies from Europe.37-39
Unilateral amaurosis as an initial symptom of juvenile idiopathic arthritis
2017, Anales de PediatriaOcular Hypotony in Patients With Juvenile Idiopathic Arthritis–Associated Uveitis
2017, American Journal of OphthalmologyRisk of Hypotony in Juvenile Idiopathic Arthritis–Associated Uveitis
2016, American Journal of OphthalmologyCitation Excerpt :In our study, hypotony was present in 9.3% of patients at presentation. This is comparable to the 1.7%–19% range reported in other cohorts.10,14,15,20 Over a median follow-up period of 5.3 years, 26 of 137 at-risk eyes in this series developed hypotony at the rate of 0.04/EY, which is similar to the rate reported for pediatric uveitis patients (0.03/EY)21 and the rate reported for JIA-associated uveitis patients within the Systemic Immunosuppressive Therapy for Eye Diseases (SITE) study (0.028/EY).15
Diagnostic and therapeutic considerations in pediatric uveitis
2024, Spektrum der Augenheilkunde
Manuscript no. 2005-1053.
The authors have no financial interest related to the subject of the article.