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IMÁGENES EN PEDIATRÍA
Descamación esofágica en pediatría. Esofagitis disecante superficial
Esophageal desquamation in pediatrics. Esophagitis dissecans superficialis
Bruna Surinyac-Ayatsa,
Autor para correspondencia
brunasuri@gmail.com

Autor para correspondencia.
, Sara Serra Fonta, Jocelyn Betancourta, Justyna Szafranskab, Susana Boronata
a Servicio de Pediatría, Hospital de la Santa Creu i Sant Pau, Barcelona, España
b Servicio de Anatomía Patológica, Hospital de la Santa Creu i Sant Pau, Barcelona, España
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          "es" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Es&#243;fago proximal &#40;20<span class="elsevierStyleHsp" style=""></span>cm arcada dentaria&#41;&#46; Se observa mucosa descamada que ocupa &#188; de la circunferencia&#46;</p>"
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Paciente de 15 a&#241;os con cl&#237;nica de epigastralgia y pirosis que presenta un reflujo gastroesof&#225;gico &#40;&#237;ndice de reflujo de 10&#44;5&#37; en pHmetr&#237;a&#41; y una esofagitis grado A en endoscopia digestiva alta &#40;EDA&#41;&#44; compatible con esofagitis p&#233;ptica&#46; Se inicia tratamiento con inhibidores de la bomba de protones &#40;IBP&#41; a 40<span class="elsevierStyleHsp" style=""></span>mg&#47;d&#237;a durante 2 meses&#44; con mejor&#237;a de la sintomatolog&#237;a&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">La paciente interrumpe el seguimiento y el tratamiento&#44; pero reconsulta a los 8 meses&#46; Se le realiza una EDA en la que se aprecia&#44; en el tercio superior y a 20<span class="elsevierStyleHsp" style=""></span>cm de arcada dentaria&#44; una zona de mucosa descamativa blanquecina que ocupa &#188; de la circunferencia esof&#225;gica &#40;<a class="elsevierStyleCrossRef" href="#fig0005">fig&#46; 1</a>&#41;&#46; El estudio histol&#243;gico &#40;<a class="elsevierStyleCrossRef" href="#fig0010">fig&#46; 2</a>&#41; result&#243; compatible con esofagitis disecante superficial &#40;EDS&#41;&#44; por lo que se pautaron IBP a dosis altas &#40;40<span class="elsevierStyleHsp" style=""></span>mg&#47;12<span class="elsevierStyleHsp" style=""></span>h&#41; durante un mes&#46; En la EDA de control a los 2 meses se confirm&#243; una normalizaci&#243;n completa&#44; tanto macrosc&#243;pica como histol&#243;gicamente&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">La EDS es una entidad muy poco frecuente en pediatr&#237;a y con escasa literatura al respecto&#46; Su etiolog&#237;a se ha relacionado con la ingesta de algunos f&#225;rmacos<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">1</span></a> y recientes estudios la asocian a las impactaciones alimentarias y a la presencia de esofagitis eosinof&#237;lica<a class="elsevierStyleCrossRefs" href="#bib0025"><span class="elsevierStyleSup">2&#44;3</span></a>&#46; Se ha postulado si la EDS podr&#237;a ser considerada un diagn&#243;stico en s&#237; misma o una secuela histol&#243;gica de una lesi&#243;n t&#243;xica o de contacto<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">3</span></a>&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">En conclusi&#243;n&#44; la EDS podr&#237;a considerarse un hallazgo endosc&#243;pico inespec&#237;fico y com&#250;n a m&#250;ltiples da&#241;os de la mucosa esof&#225;gica y con escasa implicaci&#243;n m&#233;dica&#46;</p></span>"
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          "es" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Corte histol&#243;gico de es&#243;fago proximal &#40;tinci&#243;n hematoxilina-eosina&#44; x4 aumentos&#41;&#46; Podemos observar capa superficial descamada compuesta de material paraquerat&#243;sico con necrosis coagulativa &#40;estrella roja&#41;&#44; as&#237; como la separaci&#243;n entre la mucosa viable y necr&#243;tica &#40;estrella azul&#41;&#46; Las flechas muestran las bacterias adheridas a la superficie de la mucosa&#46;</p> <p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">No se observan inclusiones v&#237;ricas ni organismos f&#250;ngicos&#46; El n&#250;mero de eosin&#243;filos intraepiteliales era &#60;15 por campo en todas las biopsias&#46;</p>"
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                    0 => array:2 [
                      "titulo" => "Pediatric sloughing esophagitis&#58; A case report and discussion"
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                            0 => "L&#46; Sun"
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                      "titulo" => "Esophagitis dissecans associated with eosinophilic esophagitis in an adolescent"
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                            0 => "M&#46;R&#46; Guerra"
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Información del artículo
ISSN: 16954033
Idioma original: Español
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