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            "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Routine immunization schedule of the Spanish Association of Pediatrics&#58; 2023 recommendations&#46;</p> <p id="spar0010" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">&#40;1&#41; Hepatitis B vaccine &#40;HB&#41;&#46;</span> Three doses of hexavalent vaccine at 2&#44; 4 and 11 months&#46; Children of HBsAg-positive mothers will be given 1 dose of vaccine and 1 dose of hepatitis B immune globulin &#40;HBIG&#41; &#40;0&#46;5&#8239;mL&#41; within 12&#8239;h of birth&#46; In the case of unknown maternal serologic status&#44; children will receive the vaccine within 12&#8239;h of birth&#44; followed by 0&#46;5&#8239;mL of HBIG&#44; preferably within 72&#8239;h of birth&#44; if maternal HBsAg-positive status is confirmed&#46; Infants vaccinated at birth will adhere to the routine schedule for the first year of life&#44; and thus will receive 4 doses of HB vaccine&#46; Unvaccinated children and adolescents should be given 3 doses of monovalent vaccine on a 0&#44; 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Inactivated poliovirus vaccine &#40;IPV&#41;&#46;</span> Four doses&#58; primary vaccination with 2 doses&#44; at 2 and 4 months&#44; and booster doses at 11 months &#40;with hexavalent vaccine&#41; and 6 years &#40;with DTaP-IPV or Tdap-IPV&#41;&#46; Children previously vaccinated with the 3&#8239;&#43;&#8239;1 schedule &#40;at 2&#44; 4&#44; 6 and 18 months&#41;&#44; require no additional doses of IPV&#46;</p> <p id="spar0025" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">&#40;4&#41; <span class="elsevierStyleItalic">Haemophilus influenzae</span> type b conjugate vaccine &#40;Hib&#41;&#46;</span> Three doses&#58; primary vaccination at 2 and 4 months and booster dose at 11 months &#40;with hexavalent vaccine&#41;&#46;</p> <p id="spar0030" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">&#40;5&#41; Pneumococcal conjugate vaccine &#40;PCV&#41;&#46;</span> Three doses&#58; the first two at 2 and 4 months&#44; with a booster dose starting at 11 months of age&#46; The vaccine recommended in Spain by the CAV-AEP continues to be the PCV13&#46;</p> <p id="spar0035" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">&#40;6&#41; Rotavirus vaccine &#40;RV&#41;&#46;</span> Two or three doses of rotavirus vaccine&#58; at 2 and 3&#8211;4 months with the monovalent vaccine or at 2&#44; 3 and 4 months or 2&#44; 3&#8211;4 and 5&#8211;6 months with the pentavalent vaccine&#46; To minimise the already low risk of intussusception&#44; vaccination must start between 6 and 12 weeks of life and be completed by 24 weeks for the monovalent vaccine and 33 weeks for the pentavalent vaccine&#46; Doses must be given at least 4 weeks apart&#46; Both vaccines may be given at the same time as any other vaccine &#40;with the exception of the oral poliovirus vaccine&#44; which is not currently distributed in Spain&#41;&#46;</p> <p id="spar0040" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">&#40;7&#41; Meningococcal B vaccine &#40;MenB&#41;&#46; 4CMenB&#46;</span> Three doses&#58; start at age 2 months&#44; with a primary series of 2 doses 2 months apart and a booster starting from age 12 months and at least 6 months after the last dose in the primary series&#46; It can be administered at the same time as other vaccines in the schedule&#44; although this could increase the likelihood of fever&#59; so it can also be administered 1 or 2 weeks apart from other injectable inactivated vaccines in the primary series to minimise potential reactogenicity&#46; The separation by 1&#8211;2 weeks is not necessary for the MenACWY&#44; MMR&#44; varicella and rotavirus vaccines&#46; For all other age groups&#44; the indication of vaccination with either vaccine &#40;4CMenB or MenB-fHbp&#41; is determined on a case-by-case basis&#44; always adhering to the minimum age authorised for the vaccine&#46;</p> <p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Vaccination is also recommended in risk groups&#58; anatomic or functional asplenia&#44; complement deficiency&#44; treatment with eculizumab or ravulizumab&#44; haematopoietic stem cell transplant recipients&#44; infection by HIV&#44; prior episode of IMD caused by any serogroup&#44; and contacts of an index case of IMD caused by serogroup B in the context of an outbreak&#46;</p> <p id="spar0050" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">&#40;8&#41; Meningococcal C conjugate vaccine &#40;MenC&#41; and meningococcal ACWY conjugate vaccine &#40;MenACWY&#41;&#46;</span> One dose of conjugate MenC-TT at age 4 months&#46; The CAV-AEP recommends 1 dose of the MenACWY conjugate vaccine at age 12 months and 11&#8211;13 years&#44; and progressive catch-up vaccination to be completed by age 18 years&#46; In ACs where the MenACWY vaccine is not included in the routine immunization schedule at 12 months&#44; if parents choose not to administer it&#44; the MenC-TT vaccine funded by the regional government must be administered instead&#46; For all other age groups&#44; the decision to vaccinate must be made on a case-by-case basis&#46;</p> <p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Administration of the MenACWY vaccine is still particularly recommended in children and adolescents that are to live in countries where the vaccine is administered at this age &#40;Canada&#44; United States&#44; Argentina&#44; Chile&#44; Saudi Arabia&#44; Australia&#44; Andorra&#44; Austria&#44; Belgium&#44; Cyprus&#44; Greece&#44; Ireland&#44; Italy&#44; Malta&#44; Netherlands&#44; United Kingdom&#44; Czech Republic&#44; San Marino and Switzerland&#41; and for children with risk factors for IMD&#58; anatomic or functional asplenia&#44; complement deficiency&#44; treatment with eculizumab or ravulizumab&#44; hematopoietic stem cell transplant recipients&#44; HIV infection&#44; prior episode of IMD caused by any serogroup&#44; and contacts of an index case of IMD caused by serogroup A&#44; C&#44; W or Y in the context of an outbreak&#46; Individuals traveling to Mecca for religious reasons and to the African meningitis belt during the dry season should also receive the MenACWY vaccine&#46;</p> <p id="spar0060" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">&#40;9&#41; Influenza vaccine&#46;</span> Vaccination recommended in all children aged 6&#8211;59 months with administration of an inactivated vaccine via the intramuscular route &#40;some can be administered via deep subcutaneous injection&#41; or&#44; from age 2 years&#44; with the intranasal live attenuated vaccine&#46; Children younger than 9 years who have not been vaccinated in previous campaigns should be given 2 doses 4 weeks apart&#44; after which they only require a single dose in subsequent seasons&#46; The dose is 0&#46;5&#8239;mL delivered intramuscularly in the case of the inactivated vaccine and 0&#46;1&#8239;mL in each nostril in the case of the attenuated vaccine&#46; Vaccination is also recommended in all risk groups and their household contacts from age 6 months&#46; Information on the risk groups for influenza is available in the <span class="elsevierStyleInterRef" id="intr0001" href="https://vacunasaep.org/documentos/manual/manual-de-vacunas">online Vaccine Manual</span> of the AEP&#46;</p> <p id="spar0065" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">&#40;10&#41; Measles&#44; mumps and rubella vaccine &#40;MMR&#41;&#46;</span> Two doses of MMR vaccine&#46; The first at age 12 months and the second at age 3&#8211;4 years&#46; The quadrivalent MMRV vaccine may be administered for the second dose&#46; In susceptible patients outside the specified ages&#44; vaccination with 2 doses of MMR at least 1 month apart is recommended&#46;</p> <p id="spar0070" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">&#40;11&#41; Varicella vaccine &#40;Var&#41;&#46;</span> Two doses&#58; the first one at 15 months &#40;although it is possible to administer from age 12 months&#41; and the second at age 3&#8211;4 years&#46; The quadrivalent vaccine &#40;MMRV&#41; may be used for the second dose&#46; Susceptible patients outside the specified ages will be vaccinated with 2 doses of monovalent Var vaccine at least 1 month apart&#44; with a recommended 12-week interval between doses in children aged less than 13 years&#46;</p> <p id="spar3080" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">&#40;12&#41; SARS-CoV-2 vaccine&#46;</span> Two vaccines are currently authorised in Spain for use from age 12 years&#58; Comirnaty-30&#8239;&#181;g &#40;Pfizer&#41; and Spikevax-100&#8239;&#181;g &#40;Moderna&#41;&#46; Another two are authorised for younger children&#58; one for children aged 5&#8211;11&#8239;years&#44; Comirnaty&#44; with a lower antigen dose &#40;Comirnaty-10&#8239;&#181;g&#41;&#44; and another for children aged 6&#8211;11&#8239;years&#44; Spikevax-100&#8239;&#181;g &#40;Moderna&#41;&#44; with administration of half the dose &#40;0&#46;25&#8239;mL&#41;&#46; Children will be given 2 doses of vaccine&#46; The Public Health Commission of Spain has decided that the 2 doses of Comirnaty 10&#8239;&#181;g and Spikevax-100&#8239;&#181;g &#40;0&#46;25&#8239;mL&#41; in children aged less than 12 years should be given 8 weeks apart&#46; If the second dose is administered in a shorter interval by mistake&#44; it will be considered valid from 21 and 28 days&#44; respectively&#46; These vaccines may be administered the same day as other vaccines or with the desired separation&#46; A booster dose is not currently recommended in children aged under 18 years&#44; except from age 5 years in children and adolescents with risk conditions or taking immunosuppressive agents&#44; who will be given a third&#44; additional dose &#40;at least 8 weeks after the last dose in the primary series&#41; and a fourth&#44; booster dose &#40;at least 5 months after the third dose&#41;&#46; Two other vaccines have been authorized by the EMA&#58; for children from 6 months to 4 years&#44; Comirnaty-3 mcg &#40;Pfizer&#41; in 3 doses and for children between 6 months and 5 years&#44; Spikevax-25 mcg &#40;Moderna&#41; in 2 doses&#46; The Public Health Commission has approved the vaccination of risk groups from 6 months of age with these vaccines&#46;</p> <p id="spar1080" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleBold">&#40;13&#41; Human papillomavirus vaccine &#40;HPV&#41;&#46;</span> Universal routine vaccination against HPV in children of any sex at age 10-12 years with 2 doses&#46; 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    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">The health care professionals that promote the biopsychosocial health of children and adolescents have witnessed a transformation in lifestyle habits across society in only a few years&#46; The traditional family structure is changing&#44; and there are different models of attachment and parenting<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a>&#44; new dietary trends and an increase in sedentary lifestyles&#44; overweight and obesity in children and adolescents<a class="elsevierStyleCrossRefs" href="#bib0010"><span class="elsevierStyleSup">2&#8211;8</span></a>&#46; Means for communicating through screens&#44; mobile phones and social networks are proliferating<a class="elsevierStyleCrossRefs" href="#bib0045"><span class="elsevierStyleSup">9&#44;10</span></a>&#46; Today&#44; there is increasing access&#44; ubiquitous and instantaneous&#44; to any type of information or images at increasingly early ages&#46; Constant interpersonal communication and information are encroaching on our free time and becoming dominant&#44; leading to progressive isolation<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">11</span></a>&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">All these changes can have a positive or negative impact in the biopsychosocial health of the most vulnerable individuals&#58; children and adolescents&#46; Therefore&#44; families need to learn how to educate children on this new reality&#44; and health care professionals have to adapt health guidance to the new social and digital environment of the patients&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">There are key subjects that must be addressed&#44; such as promoting positive and consistent parenting&#44; respect&#44; equality&#44; emotional health and healthy sexual development&#44; in addition to setting boundaries for children&#46; It is important to improve stimulation of spoken language&#44; promote adequate screen use and specify when mobile phones can be used&#46; Another essential aspect is the prevention of domestic violence and sexual abuse&#44; as prevention can reduce the probability of abuse by half<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">12</span></a>&#46; Evidence-based information must be given on novel topics such as the prevention of bullying and cyberbullying&#44; avoiding environmental pollutants and promoting environmental awareness&#46; Ongoing efforts must be made to promote physical activity and healthy dietary habits<a class="elsevierStyleCrossRefs" href="#bib0015"><span class="elsevierStyleSup">3&#44;5</span></a>&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">The World Health Organization &#40;WHO&#41; recommends promoting self-care interventions as critical elements for achieving universal health coverage&#44; promoting health and help vulnerable populations&#46; This allows individuals to have better control of their own health<a class="elsevierStyleCrossRef" href="#bib0065"><span class="elsevierStyleSup">13</span></a>&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">For all the above reasons&#44; the Asociaci&#243;n Espa&#241;ola de Pediatr&#237;a de Atenci&#243;n Primaria &#40;Spanish Association of Primary Care Paediatrics&#44; AEPap&#41; has updated its Well Child Programme &#40;WCP&#41;&#46; The new Programme for Preventive Activities in Childhood and Adolescence &#40;known as PAPI&#44; for the Spanish acronym&#41;&#44; presented in the form of a mobile application &#40;app&#41;&#44; was developed to update and expand the WCP published in 2011<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">14</span></a> to adapt it to the emerging needs of the population and of the health care professionals that provide services to children and adolescents at the primary care level&#46; The PAPI acronym is also a playful reminder by paediatricians of the need to promote equality in childcare and parenting&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Methods</span><p id="par0030" class="elsevierStylePara elsevierViewall">The WCP was updated taking into account the contributions of working groups of the AEPap with a particular focus on health guidance and preventive paediatrics&#46; The updates of the WCPs established by various public administration bodies in different autonomous communities in Spain were also reviewed&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">The AEPap is an association that represents more than 5000 primary care &#40;PC&#41; paediatricians&#46; In the years it has been operating&#44; it has developed informational tools for the general population&#44; chief of which is the Familia y Salud website that provides health guidance to families and adolescents&#46; This site has had more than 9 003 614 users and received more than 12 785 306 visits<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">15</span></a>&#46; The following working groups of the AEPap also collaborated in the development of PAPI&#58; health education&#44; social and community paediatrics&#44; attention-deficit hyperactivity disorder &#40;ADHD&#41; and psychoeducational development&#44; paediatric gastroenterology and nutrition&#44; sleep and PrevInfad &#40;prevention in paediatrics&#41;&#46; Experts in childhood vaccination and breastfeeding affiliated with the baby-friendly hospital initiative in Spain &#40;known as IHAN&#41; also participated&#46; These working groups include several experts in paediatrics that are considered leaders in their respective fields at the national level&#46; The PAPI programme has also drawn from the parenting and health guidance contents developed by the Familia y Salud and other materials produced by different working groups of the AEPap&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">Within the public health care administration&#44; some primary care management teams have published WCP documents developed in close cooperation with paediatrics associations and societies at the regional level&#46; The AEPap is a federation formed by the PC paediatrics societies of different autonomous communities&#46; At the local level&#44; some of these societies have developed their own WCPs&#44; which were reviewed during the development of PAPI&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">To get the PAPI project started&#44; a Google form was submitted in December 2020 to the spokespersons of the board of directors of the regional societies&#44; which represent more than 5000 PC paediatricians&#46; The same form was submitted to the coordinators of the 17 working groups of the AEPap&#46; The form was used to collect information on the different WCP documents developed or updated in the past 5 years and any aspects newly introduced to these programmes&#46;</p><p id="par0050" class="elsevierStylePara elsevierViewall">The programmes used in the development of PAPI were the WCP of Andalusia published in 2014<a class="elsevierStyleCrossRef" href="#bib0080"><span class="elsevierStyleSup">16</span></a>&#44; the programme of the Balearic Islands published in 2018<a class="elsevierStyleCrossRef" href="#bib0085"><span class="elsevierStyleSup">17</span></a> and the programme of the Principality of Asturias also published in 2018<a class="elsevierStyleCrossRef" href="#bib0090"><span class="elsevierStyleSup">18</span></a>&#46; The new WCP of the Basque Country had not been developed in full at the time<a class="elsevierStyleCrossRef" href="#bib0095"><span class="elsevierStyleSup">19</span></a>&#46; The Andalusian programme was selected on account of the additional topics it introduced&#44; such as positive and consistent parenting&#44; appropriate screen use&#44; stimulation of speech&#44; reading aloud&#44; promotion of drawing and prevention of sexual abuse<a class="elsevierStyleCrossRef" href="#bib0100"><span class="elsevierStyleSup">20</span></a>&#46; The programme from the Balearic Islands was selected due to its contributions in health education&#44; as it incorporated 2 workshops for parents&#58; one on positive parenting<a class="elsevierStyleCrossRef" href="#bib0105"><span class="elsevierStyleSup">21</span></a> and one for health education<a class="elsevierStyleCrossRef" href="#bib0110"><span class="elsevierStyleSup">22</span></a>&#46; The programme from Asturias was selected due to its coverage of social and community paediatrics&#46;</p><p id="par0055" class="elsevierStylePara elsevierViewall">We distributed the different interventions into 9 age groups&#44; based on the volume of specific information available&#44; with a larger number of topics in the first year of life&#44; when families and providers alike tend to have more questions and concerns &#40;<a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>&#58; age groups&#41;&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Evidence-based recommendations</span><p id="par0060" class="elsevierStylePara elsevierViewall">Part of the recommendations of the PAPI programme and regional WCPs are based on the work carried out PrevInfad&#44; a working group of paediatricians that was formed in 1990&#44; originating in the childhood and adolescence group within the Programme of Preventive Activities and Health Promotion &#40;PAPPS&#41; of the Sociedad Espa&#241;ola de Medicina Familiar y Comunitaria &#40;Spanish Society of Family and Community Medicine&#44; SEMFYC&#41;&#44; and which has been a working group of the AEPap since year 2000&#46;</p><p id="par0065" class="elsevierStylePara elsevierViewall">The PrevInfad assesses and summarises the evidence for each of the prevention activities it proposes&#44; which can be consulted at&#58; <a href="https://previnfad.aepap.org">https&#58;&#47;&#47;previnfad&#46;aepap&#46;org</a>&#46;</p><p id="par0070" class="elsevierStylePara elsevierViewall">PrevInfad uses the approach of evidence-based medicine to develop its recommendations &#40;<a class="elsevierStyleCrossRef" href="#tbl0010">Table 2</a>&#41;&#44; and the method used in their development has been published in its working manual<a class="elsevierStyleCrossRef" href="#bib0115"><span class="elsevierStyleSup">23</span></a>&#46; It grades its recommendations either with the Grading of Recommendations&#44; Assessment&#44; Development and Evaluations &#40;GRADE&#41; or the United States Preventive Services Task Force &#40;USPSTF&#41; system&#44; depending on the subject matter&#46;</p><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><p id="par0075" class="elsevierStylePara elsevierViewall">We selected some of the interventions recommended by the PrevInfad working group in Spain in addition to those of other institutions&#44; such as the USPSTF&#44; the Centers for Disease Control and Prevention &#40;CDC&#41; of the United States and the WHO&#44; synthesising the evidence for the supporting recommendations for childhood preventive interventions for primary health care endorsed by the WHO<a class="elsevierStyleCrossRefs" href="#bib0120"><span class="elsevierStyleSup">24&#44;25</span></a>&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Results and discussion</span><p id="par0080" class="elsevierStylePara elsevierViewall">In the synthesis of the evidence published by the WHO&#44; the authors found a high degree of consensus between international institutions regarding the effectiveness of the single interventions of administering vitamin D and topical fluoride through oral hygiene&#46; Consensus was more variable for the multiple interventions described to prevent sudden infant death syndrome and the prevention of unintentional injuries&#44; as evidence of their effectiveness is harder to ascertain&#46; Institutions generally agreed in recommending vision screening based on age and recommending against universal screening for language and speech delay and iron deficiency&#44; they had some differences for pulse oximetry and autism<a class="elsevierStyleCrossRef" href="#bib0120"><span class="elsevierStyleSup">24</span></a>&#46;</p><p id="par0085" class="elsevierStylePara elsevierViewall"><a class="elsevierStyleCrossRef" href="#tbl0015">Table 3</a> summarises the recommendations regarding screening&#44; prophylaxis or health guidance in the field of PC paediatrics developed by PrevInfad&#44; along with their grading based on the quality of the evidence&#59; for some interventions&#44; there was sufficient evidence to support their implementation&#44; for others&#44; there were some questions&#44; and for yet others the evidence supported a recommendation against their implementation<a class="elsevierStyleCrossRefs" href="#bib0130"><span class="elsevierStyleSup">26&#44;27</span></a>&#46;</p><elsevierMultimedia ident="tbl0015"></elsevierMultimedia><p id="par0090" class="elsevierStylePara elsevierViewall">The PAPI application covers a total of 339 topics on child and adolescent care&#44; broken down into 9 age groups that range from the neonatal period to age 13&#8722;17 years&#46; There are 194 topics offering guidance for family members on a variety of issues&#44; 31 topics for older children and adolescents and 114 topics for paediatric care providers&#46; The topics are summarised&#44; presenting a selection of the most useful advice in a user-friendly format&#46; For topics for which there was insufficient scientific evidence&#44; the contents were written by paediatric care experts that are leaders in Spain on the subjects of vaccination&#44; nutrition&#44; social paediatrics&#44; ADHD&#44; members of the team of the Familia y Salud website and members of the working group on health education&#46; Topics related to breastfeeding were written by paediatricians members of the baby-friendly hospital initiative in Spain &#40;IHAN&#41;&#46;</p><p id="par0095" class="elsevierStylePara elsevierViewall">The AEPap considers that the WCP must be implemented by the paediatric care team&#58; the paediatrician and nurse&#44; ideally&#44; a paediatric nurse<a class="elsevierStyleCrossRefs" href="#bib0140"><span class="elsevierStyleSup">28&#44;29</span></a>&#46; Organic Law 8&#47;2015 of 22 July on the amendment of the child and adolescent protection system advocates for guaranteeing protection for minors consistently throughout the state and develops on and reinforces right of minors to have their best interests upheld&#44; a fundamental principle in this field<a class="elsevierStyleCrossRefs" href="#bib0150"><span class="elsevierStyleSup">30&#44;31</span></a>&#46; In spite of these&#44; there are regions&#44; such as the autonomous community of Andalusia or certain areas of Madrid&#44; that do not have specific clinics nor paediatric nurses specifically allocated to provide these services<a class="elsevierStyleCrossRefs" href="#bib0160"><span class="elsevierStyleSup">32&#44;33</span></a>&#46;</p><p id="par0100" class="elsevierStylePara elsevierViewall">The role of nurses in monitoring growth&#44; visual acuity&#44; hearing&#44; development and other aspects&#44; administering vaccines and offering guidance in health prevention and promotion complements the work of physicians specialised in paediatric care&#46; The paediatrician is the specific provider responsible to carry out full physical examinations&#44; prescribe the vaccines appropriate for each age&#44; order diagnostic tests and prescribe any medication needed by the patient&#46; A full physical examination by the paediatrician is not necessary in every scheduled well-child visit&#44; as suggested in <a class="elsevierStyleCrossRef" href="#tbl0020">Table 4</a>&#46;</p><elsevierMultimedia ident="tbl0020"></elsevierMultimedia><p id="par0105" class="elsevierStylePara elsevierViewall">Children and adolescents will receive better care from the paediatric care team at the primary care centre if physicians and nurses work in tandem and on a 1&#58;1 ratio<a class="elsevierStyleCrossRef" href="#bib0170"><span class="elsevierStyleSup">34</span></a>&#46; At least one of each of these professionals&#44; a paediatrician and a nurse&#44; must be allocated to each caseload so that the specific competencies that fall in the scope of each of these professionals are best utilised in each programmed well-child visit<a class="elsevierStyleCrossRef" href="#bib0175"><span class="elsevierStyleSup">35</span></a>&#46; This would make it possible to assess for adequate growth and development&#44; review the vaccination schedule&#44; provide up-to-date health recommendations and revise prescriptions upon the early detection of changes in health to deliver prompt and appropriate treatment in a single visit&#46;</p><p id="par0110" class="elsevierStylePara elsevierViewall">Within the framework of PAPI&#44; the AEPap proposes that WCP activities should be carried out in specialised paediatric clinics&#44; with waiting areas separate from those of adults and designed to be more welcoming to young patients&#46;</p><p id="par0115" class="elsevierStylePara elsevierViewall">The WHO considers it essential to empower individuals&#44; families and communities to improve their own health by enabling them to care for themselves and others and providing tools to protect wellbeing&#46; Health promotion encompasses a broad range of social and environmental interventions aimed at improving and protecting the quality of life of all individuals<a class="elsevierStyleCrossRef" href="#bib0065"><span class="elsevierStyleSup">13</span></a>&#46;</p><p id="par0120" class="elsevierStylePara elsevierViewall">For all of the above&#44; the decision was made to present the PAPI as a free mobile application as a novel means for disseminating information about child and adolescent health&#46; This mobile app offers guidance on parenting for families&#44; healthy lifestyle recommendations for children and adolescents and information on how to carry out WCP checkups in each specific age group for health care professionals in paediatric PC teams &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#58; main screens of the app&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0125" class="elsevierStylePara elsevierViewall">The three main elements of primary healthcare described in the 2018 Declaration of Astana are<a class="elsevierStyleCrossRef" href="#bib0065"><span class="elsevierStyleSup">13</span></a>&#58;<ul class="elsevierStyleList" id="lis0005"><li class="elsevierStyleListItem" id="lsti0005"><span class="elsevierStyleLabel">1</span><p id="par0130" class="elsevierStylePara elsevierViewall">Meeting people&#8217;s needs through comprehensive and integrated health services &#40;including promotive&#44; protective&#44; preventive&#41;&#44; prioritizing primary care and essential public health functions&#59;</p></li><li class="elsevierStyleListItem" id="lsti0010"><span class="elsevierStyleLabel">2</span><p id="par0135" class="elsevierStylePara elsevierViewall">Systematically addressing the broader determinants of health &#40;including social&#44; economic and environmental factors as well as individual characteristics and behaviours&#41;&#59; and</p></li><li class="elsevierStyleListItem" id="lsti0015"><span class="elsevierStyleLabel">3</span><p id="par0140" class="elsevierStylePara elsevierViewall">Empowering individuals&#44; families and communities to optimize their health as advocates of policies that promote and protect health and well-being&#44; as codevelopers of health and social services and as self-carers and caregivers &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#58; WHO guideline on self-care interventions&#41;&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia></li></ul></p><p id="par0145" class="elsevierStylePara elsevierViewall">Self-care interventions give individuals more choice and improve individual autonomy when they are accessible&#44; appropriate and affordable&#46; These interventions are significant drivers of self-determination&#44; self-efficacy&#44; autonomy and active participation in their own health in both self-carers and caregivers<a class="elsevierStyleCrossRef" href="#bib0065"><span class="elsevierStyleSup">13</span></a>&#46;</p><p id="par0150" class="elsevierStylePara elsevierViewall">In its good practice statements&#44; the WHO declares that &#8220;All self-care interventions for health must be accompanied by accurate&#44; understandable and actionable information&#44; in accessible formats and languages&#44; about the intervention itself and how to link to relevant community- or facility-based healthcare services&#44; and the opportunity to interact with a health worker or a trained peer supporter to support decisions around&#44; and the use of&#44; the intervention&#8221;&#46; Ideally&#44; the paediatrician and&#47;or the nurse will provide guidance during routine checkups&#44; thus personalising the contents covered by the app for each child or adolescent<a class="elsevierStyleCrossRef" href="#bib0065"><span class="elsevierStyleSup">13</span></a>&#46;</p><p id="par0155" class="elsevierStylePara elsevierViewall">The time allocated to provide health guidance and the multiple current recommendations is never sufficient in the overcrowded primary care centres in Spain&#46; The aim in using the novel mobile application format is to extend the time that families can access parenting guidance developed by paediatricians who are leaders in their respective fields in Spain&#44; for the purpose of promoting and prolonging personalised intensive interventions&#46; Individual or group intensive interventions &#40;multiple sessions lasting 30<span class="elsevierStyleHsp" style=""></span>min or longer&#41; have been found to achieve better short- and long-term outcomes compared to short- and intermediate-length interventions<a class="elsevierStyleCrossRef" href="#bib0180"><span class="elsevierStyleSup">36</span></a>&#46;</p><p id="par0160" class="elsevierStylePara elsevierViewall">The AEPap decided to design the programme as a mobile app to facilitate and improve the delivery of information on disease prevention&#44; and to make it free to the public to provide unlimited access to parenting advice developed by PC paediatricians to every family&#46; This is a modern&#44; manageable&#44; structured and dynamic format chosen with the aim of empowering parents by delivering all contents relevant to the health of their children through a simple QR code used to download the app&#44; with no administrative red tape&#46;</p><p id="par0165" class="elsevierStylePara elsevierViewall">The application is a tool meant to palliate the lack of time and scarcity of human resources of primary care centres&#44; consolidating the health recommendations of different revisions of the WCP by age group&#46; Thus&#44; families will be able to consult the recommendations whenever they need&#44; at home or prior to attending a scheduled well-child visit with the child to be able to ask any questions they may have about them &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>&#58; Examples of topics in the app&#41;&#46;</p><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0170" class="elsevierStylePara elsevierViewall">The AEPap hopes that this new tool will prove useful to both providers and families&#46; The app is called &#8220;Salud Infantil&#8221; &#40;paediatric health&#41; and has been available for download to mobile devices since September 2022 in the App Store and the Play Store&#46; It can also be downloaded through a QR code &#40;<a class="elsevierStyleCrossRef" href="#fig0020">Fig&#46; 4</a>&#58; How to download the app&#41;&#46;</p><elsevierMultimedia ident="fig0020"></elsevierMultimedia></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0090">Funding</span><p id="par0175" class="elsevierStylePara elsevierViewall">The study did not receive any funding from the public&#44; private or non-profit sectors&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0095">Conflicts of interest</span><p id="par0180" class="elsevierStylePara elsevierViewall">The authors have no conflicts of interest to declare&#46;</p></span></span>"
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        "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Introduction</span><p id="spar0145" class="elsevierStyleSimplePara elsevierViewall">The family structure and parenting are changing in society&#44; sedentary lifestyle&#44; the use of screens and social networks is increasing&#46; Families and health professionals must learn to educate&#44; adapting their health advice to the new social and digital environment&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Materials and methods</span><p id="spar0150" class="elsevierStyleSimplePara elsevierViewall">A survey was sent to the representatives of more than 5000 paediatricians to renew the Well Child Visits Programme of the Spanish Association of Primary Care Paediatrics &#40;AEPap&#41;&#46; Contributions from preventive programmes from Andalusia&#44; the Balearic Islands and Asturias were incorporated&#46; The different interventions and advice were distributed in nine age groups&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Results</span><p id="spar0155" class="elsevierStyleSimplePara elsevierViewall">Part of the recommendations are based on the work of the PrevInfad group&#46; It uses the methodology of evidence-based medicine and performs the evaluation and synthesis of the evidence in the proposed preventive activities&#46;</p><p id="spar0160" class="elsevierStyleSimplePara elsevierViewall">The AEPap considers that the Well Child Programme should be carried out by the paediatric team&#58; the paediatrician and the nurse&#44; thus enhancing specific skills&#46;</p><p id="spar0165" class="elsevierStyleSimplePara elsevierViewall">The WHO considers it essential to empower individuals&#44; families&#44; and communities to optimize their health by making them caretakers of themselves and others&#44; equipping them with tools that protect their well-being&#46;</p></span> <span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Conclusion</span><p id="spar0170" class="elsevierStyleSimplePara elsevierViewall">Hence&#44; it was decided to capture the Well Child Programme in the format of a free APP for mobile devices&#44; as an innovative and affordable method of disseminating child and adolescent health&#46; Information is given on parenting advice for family members&#44; for children and adolescents and describes health check-ups for health workers&#46;</p></span>"
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        "resumen" => "<span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Introducci&#243;n</span><p id="spar0175" class="elsevierStyleSimplePara elsevierViewall">La estructura familiar y la crianza est&#225;n cambiando en la sociedad&#44; se incrementa el sedentarismo&#44; el uso de pantallas y de redes sociales&#46; Las familias y los profesionales sanitarios deben aprender a educar&#44; adaptando sus consejos de salud al nuevo entorno social y digital&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Material y m&#233;todos</span><p id="spar0180" class="elsevierStyleSimplePara elsevierViewall">Para renovar el Programa de Salud Infantil &#40;PSI&#41; de la Asociaci&#243;n Espa&#241;ola de Pediatr&#237;a de Atenci&#243;n Primaria &#40;AEPap&#41; se envi&#243; una encuesta a los representantes de m&#225;s de 5&#46;000 pediatras&#46; Se incorporaron aportaciones de los programas preventivos de Andaluc&#237;a&#44; Baleares y Asturias&#46; Se distribuyeron las diferentes intervenciones y consejos en nueve grupos etarios&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Resultados</span><p id="spar0185" class="elsevierStyleSimplePara elsevierViewall">Parte de las recomendaciones est&#225;n basadas en el trabajo del grupo PrevInfad&#44; llevadas a cabo con metodolog&#237;a de medicina basada en la evidencia&#44; mediante la evaluaci&#243;n y s&#237;ntesis de la evidencia de las actividades preventivas propuestas&#46;</p><p id="spar0190" class="elsevierStyleSimplePara elsevierViewall">La AEPap considera que el PSI debe realizarse por el equipo de pediatr&#237;a&#58; pediatra y enfermera&#47;o&#44; potenci&#225;ndose as&#237; las competencias espec&#237;ficas&#46;</p><p id="spar0195" class="elsevierStyleSimplePara elsevierViewall">La OMS considera primordial empoderar a las personas&#44; familias y comunidades para que optimicen su salud al convertirlas en cuidadoras de s&#237; mismas y de otros&#44; dot&#225;ndolas de herramientas que protegen el bienestar&#46;</p></span> <span id="abst0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0055">Conclusiones</span><p id="spar0200" class="elsevierStyleSimplePara elsevierViewall">Por todo ello se decide plasmar el PSI en formato de APP para dispositivos m&#243;viles gratuita&#44; como m&#233;todo innovador y asequible de divulgaci&#243;n de salud infantojuvenil&#46; Se informa sobre consejos de crianza para los familiares&#44; para los ni&#241;os&#47;as y adolescentes y describe las revisiones de salud para los sanitarios&#46;</p></span>"
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            "apendice" => "<p id="par0185" class="elsevierStylePara elsevierViewall">Marta Esther V&#225;zquez Fern&#225;ndez&#44; Catalina N&#250;&#241;ez Jim&#233;nez&#44; Ana Fierro Urturi&#44; Cristina Garc&#237;a de Ribera&#44; Elena Santamar&#237;a Marcos&#44; F&#225;tima Mu&#241;oz Velasco&#44; Margarita Escudero Lirio&#44; Mar&#237;a Alfaro Gonz&#225;lez&#44; Mar&#237;a Jos&#233; Garc&#237;a M&#233;rida&#44; Mar&#237;a Tr&#237;guez Garc&#237;a&#44; Mar&#237;a Rosa Pavo Garc&#237;a&#44; M&#46;&#170; Esther Serrano Poveda&#44; Elena Fern&#225;ndez Segura&#44; Nieves Nieto del Rinc&#243;n&#44; Carolina Hern&#225;ndez-Carrillo Rodr&#237;guez&#44; Ana Mar&#237;a Lorente Garc&#237;a Mauri&#241;o&#44; Paloma de la Calle Tejerina&#44; Ana Garach G&#243;mez&#44; Teresa Cenarro Guerrero&#44; Juan Rodr&#237;guez Delgado&#44; Esther Ru&#237;z Ch&#233;rcoles&#44; Laura Garc&#237;a Soto&#44; Jos&#233; Mar&#237;a Mengual Gil&#44; Julia Colomer Revuelta&#44; Olga Cort&#233;s Rico&#44; Mar&#237;a Jes&#250;s Esparza Olcina&#44; Jos&#233; Galve S&#225;nchez-Ventura&#44; Ana Gallego Iborra&#44; Jos&#233; Ignacio P&#233;rez Cand&#225;s&#44; &#193;ngel Carrasco Sanz&#44; Mar&#237;a de los &#193;ngeles Ord&#243;&#241;ez Alonso&#44; Narcisa Palomino Urda&#44; Manuela S&#225;nchez Echenique&#44; Ignacio Cruz Navarro&#44; Clara Garc&#237;a Cend&#243;n&#44; Judith Monta&#241;ez Arteaga&#44; Gema Perera de Le&#243;n&#44; Jos&#233; Miguel Garc&#237;a Cruz&#44; Rufino Hergueta Lend&#237;nez&#44; Cecilia Matilde G&#243;mez M&#225;laga&#44; Francisco Javier Soriano Faura&#44; Lourdes Aguilera L&#243;pez&#44; Edurne Ciriza Barea&#44; Francisco Javier Navarro Quesada&#44; &#193;ngel Hern&#225;ndez Merino&#44; Jos&#233; Murcia Garc&#237;a&#44; Mireia Cortada Gracia&#44; Ram&#243;n Ugarte L&#237;bano&#46;</p>"
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          "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Examples of topics in the app&#58;</p> <p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Health care provider profile&#58; guidance for age 1 month&#46;</p> <p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Family profile&#58; guidance for age 2&#8211;5 years&#46;</p>"
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Age 9&#8722;12 years&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Age 13&#8722;17 years&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Age groups&#46;</p>"
        ]
      ]
      5 => array:8 [
        "identificador" => "tbl0010"
        "etiqueta" => "Table 2"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0055"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">A work manual is available at <span class="elsevierStyleInterRef" id="intr0010" href="https://previnfad.aepap.org/manual-de-trabajo">https&#58;&#47;&#47;previnfad&#46;aepap&#46;org&#47;manual-de-trabajo</span><a class="elsevierStyleCrossRef" href="#bib0115"><span class="elsevierStyleSup">23</span></a>&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:1 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Framing the question&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Literature search and selection of evidence&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Evaluation and synthesis of evidence&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Statistical methods used to measure results&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Magnitude of benefit&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Magnitude of harm&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Applicability&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Development of recommendations&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Evidence-based medicine approach applied in the development of the recommendations&#46;</p>"
        ]
      ]
      6 => array:8 [
        "identificador" => "tbl0015"
        "etiqueta" => "Table 3"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0060"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">VKDB&#58; vitamin K deficiency bleeding&#44; USPSTF&#58; US Preventive Task Force&#46; Available in&#58; <span class="elsevierStyleInterRef" id="intr0020" href="http://www.uspreventiveservicestaskforce.org/Page/Name/grade-definitions">http&#58;&#47;&#47;www&#46;uspreventiveservicestaskforce&#46;org&#47;Page&#47;Name&#47;grade-definitions</span>&#46; GRADE metodolog&#237;a GRADE&#46; Available in&#58; <span class="elsevierStyleInterRef" id="intr0025" href="https://www.gradeworkinggroup.org/">https&#58;&#47;&#47;www&#46;gradeworkinggroup&#46;org&#47;</span>&#46;</p><p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">Recommendation grading categories of the USPSTF 2012&#46;</p><p id="spar0075" class="elsevierStyleSimplePara elsevierViewall">The USPSTF has defined 5 grades to assign to recommendations&#46;</p><p id="spar0080" class="elsevierStyleSimplePara elsevierViewall">A - There is high certainty that the net benefit is substantial&#46;</p><p id="spar0085" class="elsevierStyleSimplePara elsevierViewall">B - There is high certainty that the net benefit is moderate or there is moderate certainty that the net benefit is moderate to substantial&#46;</p><p id="spar0090" class="elsevierStyleSimplePara elsevierViewall">C - Fair evidence that there is likely to be only a small benefit from this service&#46;</p><p id="spar0095" class="elsevierStyleSimplePara elsevierViewall">D - There is moderate or high certainty that the service has no net benefit or that the harms outweigh the benefits&#46;</p><p id="spar0100" class="elsevierStyleSimplePara elsevierViewall">I - Evidence is lacking&#44; of poor quality&#44; or conflicting&#44; and the balance of benefits and harms cannot be determined&#46;</p><p id="spar0105" class="elsevierStyleSimplePara elsevierViewall">Assessment of recommendations with the GRADE method&#58;</p><p id="spar0110" class="elsevierStyleSimplePara elsevierViewall">a&#46; Use recommended &#8211; Strong in favour&#46;</p><p id="spar0115" class="elsevierStyleSimplePara elsevierViewall">b&#46; Use suggested &#8211; Weak in favour&#46;</p><p id="spar0120" class="elsevierStyleSimplePara elsevierViewall">c&#46; Use recommended against &#8211; Strong against&#46;</p><p id="spar0125" class="elsevierStyleSimplePara elsevierViewall">d&#46; Use discouraged &#8211; Weak against&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:1 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col">PREVINFAD recommendations&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td-with-role" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t ; entry_with_role_colgroup " colspan="2" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Recommendation grading method</th></tr><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">USPSTF&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">GRADE&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " colspan="3" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Screening</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Vision screening at 3&#8722;5 years&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">B&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Vision screening at 6&#8722;14 years&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">I&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Universal coeliac disease screening&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Weak against&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Risk group coeliac disease screening&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Strong in favour&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Universal chlamydia screening in sexually active adolescents&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">I&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Chlamydia screening in adolescents engaging in sexual risk behaviours&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">B&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Cryptorchidism&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">B&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Major depression&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">D&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Scoliosis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Weak against&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Universal screening for iron-deficiency anaemia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Strong against&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Risk group screening for iron-deficiency anaemia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Weak in favour&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Risk group screening for high cholesterol&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">I&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Hypertension&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">I&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Hearing loss &#40;newborn hearing screen&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Weak in favour&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Universal autism spectrum disorder screening&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Weak against&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Risk group autism spectrum disorder screening&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Strong in favour&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Universal developmental disorder screening&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Weak against&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Developmental disorder screening if there is clinical suspicion&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Weak in favour&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Universal tuberculosis screening&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Strong against&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Risk group tuberculosis screening&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Strong in favour&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " colspan="3" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " colspan="3" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Prophylaxis</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Vitamin D in infants under 1<span class="elsevierStyleHsp" style=""></span>year&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">B&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Vitamin D in children aged &#62;1<span class="elsevierStyleHsp" style=""></span>year in risk groups&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">B&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Vitamin D in preterm infants under 1<span class="elsevierStyleHsp" style=""></span>year&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">A&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Vitamin K for prophylaxis of VKDB of the newborn&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Strong in favour&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Iodine supplementation during pregnancy and breastfeeding&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Weak against&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " colspan="3" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " colspan="3" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Guidance</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Physical activity and sports&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Weak in favour&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Breastfeeding support&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Strong in favour&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">High cholesterol&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">B&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Prevention of hypertension&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">A&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Prevention of smoking in adolescents&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Strong in favour&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Prevention of unplanned pregnancy and sexually transmitted diseases in adolescents&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">B&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Prevention of unintentional injury at home in children&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">B&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Prevention of road traffic injuries in children&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">B&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Prevention of sudden infant death syndrome&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">A&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Prevention of sudden infant death syndrome&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">B&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Prenatal care&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">A&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
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                            0 => "M&#46; de Onis"
                            1 => "C&#46; Mart&#237;nez-Costa"
                            2 => "F&#46; Nu&#241;ez"
                            3 => "G&#46; Nguefackt-Sague"
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Journal Information
Vol. 98. Issue 1.
Pages 59.e1-59.e10 (1 January 2023)
Visits
2569
Vol. 98. Issue 1.
Pages 59.e1-59.e10 (1 January 2023)
Special Article
Open Access
We advance in health thanks to the PAPI children's health application
Avanzamos en salud gracias a la aplicación salud infantil PAPI: programa de actividades preventivas de la infancia y adolescencia
Visits
2569
Concepción Sánchez Pinaa,
Corresponding author
conchasanchezpina@gmail.com

Corresponding author.
, Jaime Javier Cuervo Valdésb, Javier Garrido Torrecillasc, María Isabel Martín Delgadod, Olga Cortés Ricoe, María Jesús Esparza Olcinaf, José María Mengual Gilg, Grupo de trabajo del Programa de Actividades Preventivas de la Infancia y Adolescencia (Grupo de trabajo del PAPI) 1
a Centro de Atención Primaria San Andrés, Madrid, Spain
b Centro de Atención Primaria Ciudad Jardín, Badajoz, Spain
c Centro de Atención Primaria de Churriana de la Vega, Granada, Spain
d Centro de Atención Primaria Santa Ponsa, Calvia, Spain
e Centro de Atención Primaria Canillejas, Madrid, Spain
f Atención Primaria, Madrid, Spain
g Centro de Atención Primaria Delicias Sur, Zaragoza, Spain
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Abstract
Introduction

The family structure and parenting are changing in society, sedentary lifestyle, the use of screens and social networks is increasing. Families and health professionals must learn to educate, adapting their health advice to the new social and digital environment.

Materials and methods

A survey was sent to the representatives of more than 5000 paediatricians to renew the Well Child Visits Programme of the Spanish Association of Primary Care Paediatrics (AEPap). Contributions from preventive programmes from Andalusia, the Balearic Islands and Asturias were incorporated. The different interventions and advice were distributed in nine age groups.

Results

Part of the recommendations are based on the work of the PrevInfad group. It uses the methodology of evidence-based medicine and performs the evaluation and synthesis of the evidence in the proposed preventive activities.

The AEPap considers that the Well Child Programme should be carried out by the paediatric team: the paediatrician and the nurse, thus enhancing specific skills.

The WHO considers it essential to empower individuals, families, and communities to optimize their health by making them caretakers of themselves and others, equipping them with tools that protect their well-being.

Conclusion

Hence, it was decided to capture the Well Child Programme in the format of a free APP for mobile devices, as an innovative and affordable method of disseminating child and adolescent health. Information is given on parenting advice for family members, for children and adolescents and describes health check-ups for health workers.

Keywords:
Primary heath care
Primary prevention
Self-care
Mobile applications
Resumen
Introducción

La estructura familiar y la crianza están cambiando en la sociedad, se incrementa el sedentarismo, el uso de pantallas y de redes sociales. Las familias y los profesionales sanitarios deben aprender a educar, adaptando sus consejos de salud al nuevo entorno social y digital.

Material y métodos

Para renovar el Programa de Salud Infantil (PSI) de la Asociación Española de Pediatría de Atención Primaria (AEPap) se envió una encuesta a los representantes de más de 5.000 pediatras. Se incorporaron aportaciones de los programas preventivos de Andalucía, Baleares y Asturias. Se distribuyeron las diferentes intervenciones y consejos en nueve grupos etarios.

Resultados

Parte de las recomendaciones están basadas en el trabajo del grupo PrevInfad, llevadas a cabo con metodología de medicina basada en la evidencia, mediante la evaluación y síntesis de la evidencia de las actividades preventivas propuestas.

La AEPap considera que el PSI debe realizarse por el equipo de pediatría: pediatra y enfermera/o, potenciándose así las competencias específicas.

La OMS considera primordial empoderar a las personas, familias y comunidades para que optimicen su salud al convertirlas en cuidadoras de sí mismas y de otros, dotándolas de herramientas que protegen el bienestar.

Conclusiones

Por todo ello se decide plasmar el PSI en formato de APP para dispositivos móviles gratuita, como método innovador y asequible de divulgación de salud infantojuvenil. Se informa sobre consejos de crianza para los familiares, para los niños/as y adolescentes y describe las revisiones de salud para los sanitarios.

Palabras clave:
Atención Primaria de Salud
Prevención primaria
Autocuidado
Aplicaciones móviles
Full Text
Introduction

The health care professionals that promote the biopsychosocial health of children and adolescents have witnessed a transformation in lifestyle habits across society in only a few years. The traditional family structure is changing, and there are different models of attachment and parenting1, new dietary trends and an increase in sedentary lifestyles, overweight and obesity in children and adolescents2–8. Means for communicating through screens, mobile phones and social networks are proliferating9,10. Today, there is increasing access, ubiquitous and instantaneous, to any type of information or images at increasingly early ages. Constant interpersonal communication and information are encroaching on our free time and becoming dominant, leading to progressive isolation11.

All these changes can have a positive or negative impact in the biopsychosocial health of the most vulnerable individuals: children and adolescents. Therefore, families need to learn how to educate children on this new reality, and health care professionals have to adapt health guidance to the new social and digital environment of the patients.

There are key subjects that must be addressed, such as promoting positive and consistent parenting, respect, equality, emotional health and healthy sexual development, in addition to setting boundaries for children. It is important to improve stimulation of spoken language, promote adequate screen use and specify when mobile phones can be used. Another essential aspect is the prevention of domestic violence and sexual abuse, as prevention can reduce the probability of abuse by half12. Evidence-based information must be given on novel topics such as the prevention of bullying and cyberbullying, avoiding environmental pollutants and promoting environmental awareness. Ongoing efforts must be made to promote physical activity and healthy dietary habits3,5.

The World Health Organization (WHO) recommends promoting self-care interventions as critical elements for achieving universal health coverage, promoting health and help vulnerable populations. This allows individuals to have better control of their own health13.

For all the above reasons, the Asociación Española de Pediatría de Atención Primaria (Spanish Association of Primary Care Paediatrics, AEPap) has updated its Well Child Programme (WCP). The new Programme for Preventive Activities in Childhood and Adolescence (known as PAPI, for the Spanish acronym), presented in the form of a mobile application (app), was developed to update and expand the WCP published in 201114 to adapt it to the emerging needs of the population and of the health care professionals that provide services to children and adolescents at the primary care level. The PAPI acronym is also a playful reminder by paediatricians of the need to promote equality in childcare and parenting.

Methods

The WCP was updated taking into account the contributions of working groups of the AEPap with a particular focus on health guidance and preventive paediatrics. The updates of the WCPs established by various public administration bodies in different autonomous communities in Spain were also reviewed.

The AEPap is an association that represents more than 5000 primary care (PC) paediatricians. In the years it has been operating, it has developed informational tools for the general population, chief of which is the Familia y Salud website that provides health guidance to families and adolescents. This site has had more than 9 003 614 users and received more than 12 785 306 visits15. The following working groups of the AEPap also collaborated in the development of PAPI: health education, social and community paediatrics, attention-deficit hyperactivity disorder (ADHD) and psychoeducational development, paediatric gastroenterology and nutrition, sleep and PrevInfad (prevention in paediatrics). Experts in childhood vaccination and breastfeeding affiliated with the baby-friendly hospital initiative in Spain (known as IHAN) also participated. These working groups include several experts in paediatrics that are considered leaders in their respective fields at the national level. The PAPI programme has also drawn from the parenting and health guidance contents developed by the Familia y Salud and other materials produced by different working groups of the AEPap.

Within the public health care administration, some primary care management teams have published WCP documents developed in close cooperation with paediatrics associations and societies at the regional level. The AEPap is a federation formed by the PC paediatrics societies of different autonomous communities. At the local level, some of these societies have developed their own WCPs, which were reviewed during the development of PAPI.

To get the PAPI project started, a Google form was submitted in December 2020 to the spokespersons of the board of directors of the regional societies, which represent more than 5000 PC paediatricians. The same form was submitted to the coordinators of the 17 working groups of the AEPap. The form was used to collect information on the different WCP documents developed or updated in the past 5 years and any aspects newly introduced to these programmes.

The programmes used in the development of PAPI were the WCP of Andalusia published in 201416, the programme of the Balearic Islands published in 201817 and the programme of the Principality of Asturias also published in 201818. The new WCP of the Basque Country had not been developed in full at the time19. The Andalusian programme was selected on account of the additional topics it introduced, such as positive and consistent parenting, appropriate screen use, stimulation of speech, reading aloud, promotion of drawing and prevention of sexual abuse20. The programme from the Balearic Islands was selected due to its contributions in health education, as it incorporated 2 workshops for parents: one on positive parenting21 and one for health education22. The programme from Asturias was selected due to its coverage of social and community paediatrics.

We distributed the different interventions into 9 age groups, based on the volume of specific information available, with a larger number of topics in the first year of life, when families and providers alike tend to have more questions and concerns (Table 1: age groups).

Table 1.

Age groups.

Newborn 
Age 1 month 
Age 2−5 months 
Age 6−11 months 
Age 12−23 months 
Age 2−5 years 
Age 6−8 years 
Age 9−12 years 
Age 13−17 years 
Evidence-based recommendations

Part of the recommendations of the PAPI programme and regional WCPs are based on the work carried out PrevInfad, a working group of paediatricians that was formed in 1990, originating in the childhood and adolescence group within the Programme of Preventive Activities and Health Promotion (PAPPS) of the Sociedad Española de Medicina Familiar y Comunitaria (Spanish Society of Family and Community Medicine, SEMFYC), and which has been a working group of the AEPap since year 2000.

The PrevInfad assesses and summarises the evidence for each of the prevention activities it proposes, which can be consulted at: https://previnfad.aepap.org.

PrevInfad uses the approach of evidence-based medicine to develop its recommendations (Table 2), and the method used in their development has been published in its working manual23. It grades its recommendations either with the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) or the United States Preventive Services Task Force (USPSTF) system, depending on the subject matter.

Table 2.

Evidence-based medicine approach applied in the development of the recommendations.

Framing the question 
Literature search and selection of evidence 
Evaluation and synthesis of evidence 
Statistical methods used to measure results 
Magnitude of benefit 
Magnitude of harm 
Applicability 
Development of recommendations 

A work manual is available at https://previnfad.aepap.org/manual-de-trabajo23.

We selected some of the interventions recommended by the PrevInfad working group in Spain in addition to those of other institutions, such as the USPSTF, the Centers for Disease Control and Prevention (CDC) of the United States and the WHO, synthesising the evidence for the supporting recommendations for childhood preventive interventions for primary health care endorsed by the WHO24,25.

Results and discussion

In the synthesis of the evidence published by the WHO, the authors found a high degree of consensus between international institutions regarding the effectiveness of the single interventions of administering vitamin D and topical fluoride through oral hygiene. Consensus was more variable for the multiple interventions described to prevent sudden infant death syndrome and the prevention of unintentional injuries, as evidence of their effectiveness is harder to ascertain. Institutions generally agreed in recommending vision screening based on age and recommending against universal screening for language and speech delay and iron deficiency, they had some differences for pulse oximetry and autism24.

Table 3 summarises the recommendations regarding screening, prophylaxis or health guidance in the field of PC paediatrics developed by PrevInfad, along with their grading based on the quality of the evidence; for some interventions, there was sufficient evidence to support their implementation, for others, there were some questions, and for yet others the evidence supported a recommendation against their implementation26,27.

Table 3.

Summary of the PrevInfad recommendations, 2022 update https://previnfad.aepap.org/.

PREVINFAD recommendations  Recommendation grading method
  USPSTF  GRADE 
Screening
Vision screening at 3−5 years   
Vision screening at 6−14 years   
Universal coeliac disease screening    Weak against 
Risk group coeliac disease screening    Strong in favour 
Universal chlamydia screening in sexually active adolescents   
Chlamydia screening in adolescents engaging in sexual risk behaviours   
Cryptorchidism   
Major depression   
Scoliosis    Weak against 
Universal screening for iron-deficiency anaemia    Strong against 
Risk group screening for iron-deficiency anaemia    Weak in favour 
Risk group screening for high cholesterol   
Hypertension   
Hearing loss (newborn hearing screen)    Weak in favour 
Universal autism spectrum disorder screening    Weak against 
Risk group autism spectrum disorder screening    Strong in favour 
Universal developmental disorder screening    Weak against 
Developmental disorder screening if there is clinical suspicion    Weak in favour 
Universal tuberculosis screening    Strong against 
Risk group tuberculosis screening    Strong in favour 
Prophylaxis
Vitamin D in infants under 1year   
Vitamin D in children aged >1year in risk groups   
Vitamin D in preterm infants under 1year   
Vitamin K for prophylaxis of VKDB of the newborn    Strong in favour 
Iodine supplementation during pregnancy and breastfeeding    Weak against 
Guidance
Physical activity and sports    Weak in favour 
Breastfeeding support    Strong in favour 
High cholesterol   
Prevention of hypertension   
Prevention of smoking in adolescents    Strong in favour 
Prevention of unplanned pregnancy and sexually transmitted diseases in adolescents   
Prevention of unintentional injury at home in children   
Prevention of road traffic injuries in children   
Prevention of sudden infant death syndrome   
Prevention of sudden infant death syndrome   
Prenatal care   

VKDB: vitamin K deficiency bleeding, USPSTF: US Preventive Task Force. Available in: http://www.uspreventiveservicestaskforce.org/Page/Name/grade-definitions. GRADE metodología GRADE. Available in: https://www.gradeworkinggroup.org/.

Recommendation grading categories of the USPSTF 2012.

The USPSTF has defined 5 grades to assign to recommendations.

A - There is high certainty that the net benefit is substantial.

B - There is high certainty that the net benefit is moderate or there is moderate certainty that the net benefit is moderate to substantial.

C - Fair evidence that there is likely to be only a small benefit from this service.

D - There is moderate or high certainty that the service has no net benefit or that the harms outweigh the benefits.

I - Evidence is lacking, of poor quality, or conflicting, and the balance of benefits and harms cannot be determined.

Assessment of recommendations with the GRADE method:

a. Use recommended – Strong in favour.

b. Use suggested – Weak in favour.

c. Use recommended against – Strong against.

d. Use discouraged – Weak against.

The PAPI application covers a total of 339 topics on child and adolescent care, broken down into 9 age groups that range from the neonatal period to age 13−17 years. There are 194 topics offering guidance for family members on a variety of issues, 31 topics for older children and adolescents and 114 topics for paediatric care providers. The topics are summarised, presenting a selection of the most useful advice in a user-friendly format. For topics for which there was insufficient scientific evidence, the contents were written by paediatric care experts that are leaders in Spain on the subjects of vaccination, nutrition, social paediatrics, ADHD, members of the team of the Familia y Salud website and members of the working group on health education. Topics related to breastfeeding were written by paediatricians members of the baby-friendly hospital initiative in Spain (IHAN).

The AEPap considers that the WCP must be implemented by the paediatric care team: the paediatrician and nurse, ideally, a paediatric nurse28,29. Organic Law 8/2015 of 22 July on the amendment of the child and adolescent protection system advocates for guaranteeing protection for minors consistently throughout the state and develops on and reinforces right of minors to have their best interests upheld, a fundamental principle in this field30,31. In spite of these, there are regions, such as the autonomous community of Andalusia or certain areas of Madrid, that do not have specific clinics nor paediatric nurses specifically allocated to provide these services32,33.

The role of nurses in monitoring growth, visual acuity, hearing, development and other aspects, administering vaccines and offering guidance in health prevention and promotion complements the work of physicians specialised in paediatric care. The paediatrician is the specific provider responsible to carry out full physical examinations, prescribe the vaccines appropriate for each age, order diagnostic tests and prescribe any medication needed by the patient. A full physical examination by the paediatrician is not necessary in every scheduled well-child visit, as suggested in Table 4.

Table 4.

Proposed checkup calendar.

Checkup  3−7 d  15 d–1 m  2 m  4 m  6 m  9 m–11 ma  12 m 
Nurse 
Paediatrician         
15 months  15 m–18 ma  2 y  4 y  6 y